Found 43 matching trials
Effects of Titrated Oral Tolvaptan 15-60 mg Once Daily (QD) on Cognitive and Neurological Function in Elderly Hyponatremic Patients
PHASE3Demonstrate an improvement in the composite scores of validated neurocognit...
Location
Sarah. S. Olelewe, MD
Comparison of Oral or Intravenous Thiazides vs Tolvaptan in Diuretic Resistant Decompensated Heart Failure
PHASE4Broad Objectives: To determine the comparative efficacy of commonly employe...
Location
Vanderbilt University Medical Center
A Study of HRS-9057 in Patients With Heart Failure and Volume Overload
PHASE1The study is an open-label, Tolvaptan-controlled Phase I study to evaluate ...
Location
The Second Affiliated Hospital of Guangzhou Medical University
EVEREST: Efficacy of Vasopressin Antagonism in hEart failuRE: Outcome Study With Tolvaptan
PHASE3The purpose of this study is to compare the effectiveness of tolvaptan or p...
Location
University of Alabama at Birmingham
The Role of Vasopressin Antagonism on Renal Sodium Handling
PHASE1Vasopressin has primarily been considered to be a water and osmosis regulat...
Location
Multiple Locations
A Multicenter Trial to Investigate the Efficacy and Safety of Tolvaptan in Patients With Hyponatremia in SIADH
PHASE3The objective of this study is to investigate the efficacy and safety of to...
Location
Multiple Locations
Effect of Tolvaptan on Mid- to Long-term Prognosis of Heart Failure Patients
PHASE4One tolvaptan 15 mg tablet or placebo tablet will be orally administered on...
Location
Multiple Locations
Tolvaptan Open-label Pilot Efficacy, Tolerability, and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
PHASE2This study's purpose is to evaluate the long-term safety of open-label tolv...
Location
University of Colorado
Short-term Renal Hemodynamic Effects of Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
PHASE2The purpose of the trial was to determine the short-term effects of tolvapt...
Location
University Medical Center Groningen
Outcome and Treatment Quality Study of Tolvaptan to Treat Hyponatremia in Patients With Heart Failure
PHASE4The objective is to evaluate the efficacy and safety on the tolvaptan for i...
Location
Seoul National University Bundang Hospital